| Item Type | Name |
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Academic Article
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Activation of stat3 in human melanoma promotes brain metastasis.
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Academic Article
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Aberrant FoxM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells.
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Academic Article
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Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.
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Academic Article
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Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis.
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Academic Article
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Identification of necrosis-associated genes in glioblastoma by cDNA microarray analysis.
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Academic Article
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Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stress.
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Academic Article
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FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells.
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Academic Article
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Aberrant NF-kappaB activity is critical in focal necrosis formation of human glioblastoma by regulation of the expression of tissue factor.
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Academic Article
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FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells.
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Academic Article
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FoxM1B regulates NEDD4-1 expression, leading to cellular transformation and full malignant phenotype in immortalized human astrocytes.
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Academic Article
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Caveolin-1 upregulation mediates suppression of primary breast tumor growth and brain metastases by stat3 inhibition.
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Academic Article
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FoxM1 promotes ?-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis.
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Academic Article
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Expression of activated signal transducer and activator of transcription 3 predicts expression of vascular endothelial growth factor in and angiogenic phenotype of human gastric cancer.
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Concept
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Humans
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Concept
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beta Catenin
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Concept
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Protein Binding
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Concept
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Tumor Burden
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Concept
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Brain Neoplasms
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Concept
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DNA-Binding Proteins
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Concept
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Transforming Growth Factor beta
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Concept
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Interferon-beta
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Concept
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Blood-Brain Barrier
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Concept
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NF-kappa B
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Concept
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Brain
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Concept
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Proto-Oncogene Proteins B-raf
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Concept
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Biomarkers, Tumor
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Concept
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Mice, Knockout
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Concept
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Animals
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Concept
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Proto-Oncogene Proteins c-bcl-2
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Concept
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Blotting, Northern
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Concept
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Aged
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Concept
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BALB 3T3 Cells
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Concept
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Calcium-Binding Proteins
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Concept
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Binding Sites
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Concept
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Antibodies, Blocking
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Concept
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Urinary Bladder Neoplasms
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Concept
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Body Weight
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred C3H
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Concept
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Blotting, Western
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Concept
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Mice, Nude
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Concept
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Adenoviridae
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Concept
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I-kappa B Proteins
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Concept
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Breast Neoplasms
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Concept
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Specific Pathogen-Free Organisms
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Concept
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Homozygote
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Concept
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Mice
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Concept
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Core Binding Factor Alpha 3 Subunit
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Concept
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Models, Biological
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Concept
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Middle Aged
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Concept
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Genetic Vectors
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Concept
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Base Sequence
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Transgenic
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Academic Article
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Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-?-dependent cancer metastasis.
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Academic Article
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Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.
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Academic Article
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Dominant-negative transcription factor AP-2 augments SB-2 melanoma tumor growth in vivo.
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Academic Article
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Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells.
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Academic Article
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Contribution of nitric oxide-mediated apoptosis to cancer metastasis inefficiency.
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Academic Article
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Expression of autocrine motility factor correlates with the angiogenic phenotype of and poor prognosis for human gastric cancer.
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Academic Article
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Combining betulinic acid and mithramycin a effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesis.
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Academic Article
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A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis.
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Academic Article
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The critical role of dysregulated FOXM1-PLAUR signaling in human colon cancer progression and metastasis.
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Academic Article
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Dysregulated expression of FOXM1 isoforms drives progression of pancreatic cancer.
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Academic Article
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Enforced c-KIT expression renders highly metastatic human melanoma cells susceptible to stem cell factor-induced apoptosis and inhibits their tumorigenic and metastatic potential.
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Academic Article
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Procathepsin-L, a proteinase that cleaves human C3 (the third component of complement), confers high tumorigenic and metastatic properties to human melanoma cells.
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Academic Article
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Cooperation between transcription factor AP-1 and NF-kappaB in the induction of interleukin-8 in human pancreatic adenocarcinoma cells by hypoxia.
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Academic Article
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Nuclear factor-kappaB activity correlates with growth, angiogenesis, and metastasis of human melanoma cells in nude mice.
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Academic Article
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Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis.
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Academic Article
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Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis.
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Academic Article
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A novel model system for studying the double-edged roles of nitric oxide production in pancreatic cancer growth and metastasis.
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Academic Article
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Vascular endothelial growth factor expression promotes the growth of breast cancer brain metastases in nude mice.
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Academic Article
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Drastic down-regulation of Kr?ppel-like factor 4 expression is critical in human gastric cancer development and progression.
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Academic Article
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Loss of RUNX3 expression significantly affects the clinical outcome of gastric cancer patients and its restoration causes drastic suppression of tumor growth and metastasis.
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Academic Article
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STAT3 as a central regulator of tumor metastases.
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Academic Article
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Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity.
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Academic Article
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Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice.
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Academic Article
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FoxM1: a potential drug target for glioma.
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Academic Article
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FoxM1 inhibition sensitizes resistant glioblastoma cells to temozolomide by downregulating the expression of DNA-repair gene Rad51.
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Academic Article
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FoxM1 and Wnt/?-catenin signaling in glioma stem cells.
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Academic Article
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Suppression of tumor growth and metastasis of murine renal adenocarcinoma by syngeneic fibroblasts genetically engineered to secrete the JE/MCP-1 cytokine.
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Academic Article
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Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells.
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Academic Article
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Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis.
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Academic Article
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Destruction of bystander cells by tumor cells transfected with inducible nitric oxide (NO) synthase gene.
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Academic Article
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Expression of MCAM/MUC18 by human melanoma cells leads to increased tumor growth and metastasis.
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Academic Article
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Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.
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Academic Article
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Interleukin 10 suppresses tumor growth and metastasis of human melanoma cells: potential inhibition of angiogenesis.
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Academic Article
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Inhibition of tumor growth and metastasis of human melanoma by intracellular anti-ATF-1 single chain Fv fragment.
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Academic Article
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Level of interleukin-8 expression by metastatic human melanoma cells directly correlates with constitutive NF-kappaB activity.
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Academic Article
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Contributions of stromal metalloproteinase-9 to angiogenesis and growth of human ovarian carcinoma in mice.
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Academic Article
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Nuclear factor-kappaB mediates angiogenesis and metastasis of human bladder cancer through the regulation of interleukin-8.
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Academic Article
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Response of non-small cell lung cancer cells to the inhibitors of phosphatidylinositol 3-kinase/Akt- and MAPK kinase 4/c-Jun NH2-terminal kinase pathways: an effective therapeutic strategy for lung cancer.
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Academic Article
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The biology of metastasis to a sanctuary site.
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Academic Article
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Constitutive NF-kappaB activity regulates the expression of VEGF and IL-8 and tumor angiogenesis of human glioblastoma.
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Academic Article
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Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.
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Academic Article
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SRC family kinases as novel therapeutic targets to treat breast cancer brain metastases.
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Academic Article
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Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells.
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Academic Article
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Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2.
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Academic Article
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Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis.
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Academic Article
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Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the murine IFN-beta gene: possible role of nitric oxide.
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Academic Article
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Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8.
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Academic Article
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Fully human antibodies to MCAM/MUC18 inhibit tumor growth and metastasis of human melanoma.
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Academic Article
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Nitric oxide synthase II suppresses the growth and metastasis of human cancer regardless of its up-regulation of protumor factors.
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Academic Article
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Critical role and regulation of transcription factor FoxM1 in human gastric cancer angiogenesis and progression.
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Academic Article
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Dysregulated Kr?ppel-like factor 4 and vitamin D receptor signaling contribute to progression of hepatocellular carcinoma.
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Academic Article
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Down-regulation of microRNA-494 via loss of SMAD4 increases FOXM1 and ?-catenin signaling in pancreatic ductal adenocarcinoma cells.
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Academic Article
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Abnormalities in the CDKN2 (p16INK4/MTS-1) gene in human melanoma cells: relevance to tumor growth and metastasis.
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Academic Article
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Synergistic therapy of human ovarian carcinoma implanted orthotopically in nude mice by optimal biological dose of pegylated interferon alpha combined with paclitaxel.
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Academic Article
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Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer.
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Academic Article
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Altered expression of transcription factor Sp1 critically impacts the angiogenic phenotype of human gastric cancer.
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Academic Article
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Cerebral metastases from malignant melanoma: current treatment strategies, advances in novel therapeutics and future directions.
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Academic Article
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FOXM1 promotes the warburg effect and pancreatic cancer progression via transactivation of LDHA expression.
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Academic Article
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PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.
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Academic Article
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Activation of vitamin D receptor signaling downregulates the expression of nuclear FOXM1 protein and suppresses pancreatic cancer cell stemness.
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Academic Article
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Tumour suppressor TRIM33 targets nuclear ?-catenin degradation.
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Academic Article
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FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells.
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Academic Article
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Forkhead Box M1 Is Essential for Nuclear Localization of Glioma-associated Oncogene Homolog 1 in Glioblastoma Multiforme Cells by Promoting Importin-7 Expression.
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Academic Article
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Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.
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Academic Article
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Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells
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Academic Article
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Merlin/NF2 suppresses pancreatic tumor growth and metastasis by attenuating the FOXM1-mediated Wnt/β-catenin signaling
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Academic Article
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Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22
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Academic Article
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FoxM1 promotes breast tumorigenesis by activating PDGF-A and forming a positive feedback loop with the PDGF/AKT signaling pathway
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Concept
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NF-KappaB Inhibitor alpha
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Concept
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Forkhead Box Protein M1
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